• +91 9971497814
  • info@interviewmaterial.com

Computer Interview Questions Answers

Question -

What is the significance of juxta glomerular apparatus (JGA) in kidney function?



Answer -

Juxta glomerular apparatus (JGA) is a special sensitive region formed by cellular modifications in the distal convoluted tubule and the afferent arteriole at the location of their contact. The JGA plays a complex regulatory role. A fall in glomerular blood flow/ glomerular blood pressure/GFR can activate the JG cells to release renin which converts angiotensinogen in blood to angiotensin I and further to angiotensin II. Angiotensin II, being a powerful vasoconstrictor, increases the glomerular blood pressure and thereby GFR. Angiotensin II also activates the adrenal cortex to release aldosterone. Aldosterone causes reabsorption of Na+ and water from the distal parts of the tubule. This also leads to an increase in blood pressure and GFR.

Comment(S)

Show all Coment

Leave a Comment




Selected

 

Computer Contributors

Aquarian Infotech System
Devraj Nagar
krishan
Rajeev Katiyar
Rashmi
Sandeep Saxena
Yes Baroda

Share your email for latest updates

Name:
Email:

Our partners